Pennsylvania 6-5000, (212-736-5000),

is the inspiration for the Jerry Gray composition of the same name (with lyrics later added by Carl Sigman). The most popular version was performed by Glenn Miller, with the Andrews Sisters' version not far behind.
For the last several decades, when callers dialed the hotel they would hear the Glenn Miller recording until an operator answered. This bit of nostalgia was discontinued in 2012, and operators answer all calls.

William Faulkner stayed at The Hotel Pennsylvania while writing one of his many novels,including notes for his  book ,"The Wild Palms." The Chef salad may have been created by Hotel Pennsylvania head chef Jacques Roser in the 1920s.Most notably On November 28, 1953, biochemist Dr. Frank Olson crashed through a window of the hotel Pennsylvania, (then the Statler Hotel) and fell over 150 feet (46 m) to the sidewalk below where he died. The New York City Police Department reported Olson’s death as a suicide. In 1975, documents released by an American Presidential-appointed commission revealed that, days before his death, Olsen had surreptitiously been dosed with LSD. Twenty-years later, further investigation into Olson’s death revealed that there was ample reason to believe that he had been murdered for being Treasonous to the USA.