Efforts to identify biomarkers that explain the pathophysiology of early adverse life events are complicated by a variety of factors including ethical considerations, lack of experimental control over the subject’s environment and genetic background and inaccessibility of primary tissues required for analysis. Therefore, the use of animal models provides a complementary approach for understanding the processes by which maternal behavior during pregnancy and the postpartum period influences the physiological and psychological health of offspring, resulting in the development of behavioral and emotional disorders. Clearly, this is a highly complex area of study, as there are a multitude of psychosocial, environmental and biological processes involved in parenting behavior.
We start by revisiting the intellect augmentation framework proposed by Doug Engelbart over five decades ago [Engelbart, 1962] by placing uniform artifacts.
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