Self-disclosure of stigmatized conditions is known to yield therapeutic beneits. Social media sites are emerging as promising platforms enabling disclosure around a variety of stigmatized concerns, including mental illness. What kind of behavioral changes precede and follow such disclosures? Do the therapeutic benefits of opening up manifest in these changes? We address these questions by focusing on disclosures of schizophrenia diagnoses made on Twitter. We adopt a clinically grounded quantitative approach to irst identify temporal phases around disclosure during which symptoms of schizophrenia are likely to be signiicant.